Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Mw; 54,000
HEK293 細胞を,Ser/Thr phosphatase 阻害剤のcalyculin A,またはTyr phosphatase 阻害剤のpervanadateで処理した後,ATF2のリン酸化状態の変化を Zn2+-Phos-tag SDS-PAGEで調べています。
Zn2+ -Phos-tag: 25µM
Polyacrylamide: 8.5%(w/v)