Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Mw; 43,000
HEK293 細胞を,Ser/Thr phosphatase 阻害剤のcalyculin A,またはTyr phosphatase 阻害剤のpervanadateで処理した後,p53のリン酸化状態の変化を Zn2+-Phos-tag SDS-PAGEで調べています。
None
Zn2+ -Phos-tag: 25µM
Polyacrylamide: 8.5%(w/v)